
Ricin.
It's an extremely EFFECTIVE poison.
Breaking Bad Season 2, Episode 1

I described your lovemaking
as aloof, but EFFECTIVE.
The Big Bang Theory Season 4, Episode 20

one of the most EFFECTIVE
techniques for moving on
The Big Bang Theory Season 7, Episode 20

SHELDON:
It was obviously EFFECTIVE.
The Big Bang Theory Season 1, Episode 16

that saying "pew, pew, pew"
isn't as EFFECTIVE
The Big Bang Theory Season 5, Episode 19